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A novel method to assess the incident angle and the LET of protons using a compact single-layer Timepix detector
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SYSNO ASEP 0559791 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title A novel method to assess the incident angle and the LET of protons using a compact single-layer Timepix detector Author(s) Nabha, R. (BE)
Van Hoey, O. (BE)
Granja, C. (CZ)
Parisi, A. (BE)
De Saint-Hubert, M. (BE)
Struelens, L. (BE)
Oancea, C. (CZ)
Sterpin, E. (BE)
Zach, Václav (UJF-V) SAI, ORCID
Štursa, Jan (UJF-V) RID, ORCID
Rucinski, A. (PL)
Gajewski, J. (PL)
Stasica, P. (PL)
Vanhavere, F. (BE)Number of authors 14 Article number 110349 Source Title Radiation Physics and Chemistry. - : Elsevier - ISSN 0969-806X
Roč. 199, OCT (2022)Number of pages 11 s. Publication form Print - P Language eng - English Country GB - United Kingdom Keywords Timepix ; Protons ; LET ; Particle therapy ; Directional detection ; Particle tracking ; Semiconductor pixel detector OECD category Nuclear related engineering Research Infrastructure CANAM II - 90056 - Ústav jaderné fyziky AV ČR, v. v. i. Method of publishing Limited access Institutional support UJF-V - RVO:61389005 UT WOS 000828304000003 EID SCOPUS 85145806383 DOI 10.1016/j.radphyschem.2022.110349 Annotation Particle therapy can largely benefit from the detailed and wide-range spectrometric and directional characterization of energetic charged particles provided by compact Timepix detectors. Among several physical quantities that can be derived, the assessment of the linear energy transfer (LET) which is based on the deposited energy and particle's track length remains challenging. Due to the detector's pixel pitch, sensor thickness and charge sharing effect, an accurate estimation of the particle's incident angle and hence the track length, has been limited to particles with incident angles greater than 20 with respect to the normal of the sensor layer. This is critical for clinical beams which are highly directional, and measurements with radiation detectors are generally performed with sensitive volumes orthogonally placed with respect to the beam direction. In this work, we present a novel method in which we exploit the morphological cluster parameters to derive the proton's incident angle, thus enabling a precise directional reconstruction over the full field-of-view 2 pi (solid angle), and within 2 from the reference angles for Timepix detectors with 300 and 500 mu m thick Si sensors. As a consequence, the calculation of the track length was also improved, resulting in a more precise LET estimation. The experimental LET spectra and the frequency-averaged LET (LETF) were compared against Monte Carlo simulations using TOPAS for a wide range of proton energies (12 MeV-200 MeV) and incident angles (0-85 & DEG). An agreement within 12% was found between measured and simulated LETF. A comparison with LET values based on the PSTAR database also showed an agreement within 10%. We demonstrated the feasibility of a precise LET calculation and directional response with an improved angular resolution down to normal incidence using a single-layer Timepix detector, while avoiding the use of a stacked telescope array. Workplace Nuclear Physics Institute Contact Markéta Sommerová, sommerova@ujf.cas.cz, Tel.: 266 173 228 Year of Publishing 2023 Electronic address https://doi.org/10.1016/j.radphyschem.2022.110349
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