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Deferasirox pyridine solvate and its Cu(II) complex: Synthesis, crystal structure, Hirshfeld surface analysis, antimicrobial assays and antioxidant activity
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SYSNO ASEP 0555827 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Deferasirox pyridine solvate and its Cu(II) complex: Synthesis, crystal structure, Hirshfeld surface analysis, antimicrobial assays and antioxidant activity Author(s) Zandvakili, T. (IR)
Fatemi, S.J. (IR)
Ebrahimipour, S.Y. (IR)
Ebrahimnejad, H. (IR)
Castro, J. (ES)
Dušek, Michal (FZU-D) RID, ORCID, SAI
Eigner, Václav (FZU-D) RID, ORCIDNumber of authors 7 Article number 131525 Source Title Journal of Molecular Structure. - : Elsevier - ISSN 0022-2860
Roč. 1249, Feb (2022)Number of pages 13 s. Language eng - English Country NL - Netherlands Keywords deferasirox pyridine solvate ; FTIR ; X-ray diffraction ; crystal structure ; antimicrobial activities Subject RIV BM - Solid Matter Physics ; Magnetism OECD category Condensed matter physics (including formerly solid state physics, supercond.) R&D Projects GA18-10504S GA ČR - Czech Science Foundation (CSF) Research Infrastructure CzechNanoLab - 90110 - Vysoké učení technické v Brně Method of publishing Limited access Institutional support FZU-D - RVO:68378271 UT WOS 000710136900017 EID SCOPUS 85116608571 DOI 10.1016/j.molstruc.2021.131525 Annotation Deferasirox pyridine solvate [(DFX)(py)] and its Cu(II) complex [Cu(DFX)(py)], (DFX = deferasirox, py = pyridine) were synthesized and characterized using several techniques such as elemental analysis, Fourier-transform infrared (FTIR), molar conductivity and vibrating sample magnetometer (VSM). In ad- dition, the structure of both compounds was determined using single-crystal X-ray diffraction method. Antimicrobial activities of the synthesized com- pounds were investigated against Staphylococcus aureus, Bacillus cereus, Escherichia coli , and Pseudomonas aeruginosa bacteria. Likewise, the antib iofilm activity of these compounds was investigated against S. au- reus and P. aeruginosa bacteria. Workplace Institute of Physics Contact Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Year of Publishing 2023 Electronic address https://doi.org/10.1016/j.molstruc.2021.131525
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