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Role of miR-653 and miR-29c in downregulation of CYP1A2 expression in hepatocellular carcinoma
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SYSNO ASEP 0555407 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Role of miR-653 and miR-29c in downregulation of CYP1A2 expression in hepatocellular carcinoma Author(s) Krkoška, Martin (BFU-R) ORCID
Nekvindová, J. (CZ)
Nevědělová, Kateřina (BFU-R)
Zubanova, V. (CZ)
Radová, L. (CZ)
Vondráček, Jan (BFU-R) RID, ORCID
Herudková, Jarmila (BFU-R)
Slabý, O. (CZ)
Kiss, I. (CZ)
Bohovicova, L. (CZ)
Fabián, P. (CZ)
Tylichová, Zuzana (BFU-R) ORCID
Kala, Z. (CZ)
Kysela, P. (CZ)
Ostrizkova, L. (CZ)
Palička, V. (CZ)
Vaculová, Alena (BFU-R) RID, ORCIDNumber of authors 17 Source Title Pharmacological Reports. - : Springer - ISSN 1734-1140
Roč. 74, č. 1 (2022), s. 148-158Number of pages 11 s. Publication form Print - P Language eng - English Country PL - Poland Keywords aryl-hydrocarbon receptor ; tumor-suppressor ; human liver ; posttranscriptional regulation ; cell-line ; cytochrome-p450 OECD category Pharmacology and pharmacy R&D Projects NV17-28231A GA MZd - Ministry of Health (MZ) Method of publishing Limited access Institutional support BFU-R - RVO:68081707 UT WOS 000718694600001 EID SCOPUS 85119055842 DOI https://doi.org/10.1007/s43440-021-00338-9 Annotation Background Hepatocellular carcinoma (HCC) is a major contributor to the worldwide cancer burden. Recent studies on HCC have demonstrated dramatic alterations in expression of several cytochrome P450 (CYP) family members that play a crucial role in biotransformation of many drugs and other xenobiotics, however, the mechanisms responsible for their deregulation remain unclear. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2022 Electronic address https://link.springer.com/article/10.1007/s43440-021-00338-9
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