Number of the records: 1
The anti-depressive effects of ultra-high static magnetic field
- 1.
SYSNO ASEP 0552056 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title The anti-depressive effects of ultra-high static magnetic field Author(s) Lv, Y. (CN)
Fan, Y. (CN)
Tian, X. (CN)
Yu, B. (CN)
Song, C. (CN)
Feng, C. (CN)
Zhang, L. (CN)
Ji, X. (CN)
Zablotskii, Vitalii (FZU-D) ORCID
Zhang, X. (CN)Number of authors 10 Source Title Journal of Magnetic Resonance Imaging. - : Wiley - ISSN 1053-1807
Roč. 56, č. 2 (2022), s. 354-365Number of pages 12 s. Language eng - English Country US - United States Keywords ultra-high field magnetic resonance imaging ; static magnetic field ; safety ; depression ; behavioral tests Subject RIV BM - Solid Matter Physics ; Magnetism OECD category Particles and field physics Method of publishing Limited access Institutional support FZU-D - RVO:68378271 UT WOS 000731302200001 EID SCOPUS 85121435857 DOI https://doi.org/10.1002/jmri.28035 Annotation Compared to the sham group, healthy C57/6 mice spent more time in the center area (35.12 ± 4.034, increased by 47.19%) in open field test and improved novel index (0.6201 ± 0.02522, increased by 16.76%) in three-chambered social test a few weeks after 1 hour 11.1–33.0 T SMF exposure. 7 T SMF exposure for 8 hours alleviated the depression state of depression mice, including less immobile time in tail suspension test (58.32% reduction) and higher sucrose preference (increased by 8.80%). Brain tissue analysis shows that 11.1–33.0 T and 7 T SMFs can increase oxytocin by 164.65% and 36.03%, respectively. Moreover, the c-Fos level in hippocampus region was increased by 14.79%. 11.1–33.0 T SMFs exposure for 1 hour or 7 T SMF exposure for 8 hours did not have detrimental effects on healthy or depressed mice. Instead, these ultra-high field SMFs have anti-depressive potentials. Workplace Institute of Physics Contact Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Year of Publishing 2023 Electronic address https://doi.org/10.1002/jmri.28035
Number of the records: 1