The hulks and the deadpools of the cytokinin universe: A dual strategy for cytokinin production, translocation, and signal transduction

0544196 - ÚEB 2022 RIV CH eng J - Journal Article
Hluska, Tomáš - Hlusková, Lucia - Emery, R. J. N.
The hulks and the deadpools of the cytokinin universe: A dual strategy for cytokinin production, translocation, and signal transduction.
Biomolecules. Roč. 11, č. 2 (2021), č. článku 209. E-ISSN 2218-273X
R&D Projects: GA ČR(CZ) GA19-12262S; GA MŠMT(CZ) EF16_019/0000738
Institutional support: RVO:61389030
Keywords : Aromatic cytokinins * Cis-zeatin * Cytokinin biosynthesis * Cytokinin oxi-dase/dehydrogenase * Cytokinin signalling * Cytokinin transport * Cytokinins * Hulk/Dead-pool * Isopentenyl transferase
OECD category: Plant sciences, botany
Impact factor: 6.064, year: 2021
Method of publishing: Open access
http://doi.org/10.3390/biom11020209

Cytokinins are plant hormones, derivatives of adenine with a side chain at the N6-position. They are involved in many physiological processes. While the metabolism of trans-zeatin and iso-pentenyladenine, which are considered to be highly active cytokinins, has been extensively studied, there are others with less obvious functions, such as cis-zeatin, dihydrozeatin, and aromatic cyto-kinins, which have been comparatively neglected. To help explain this duality, we present a novel hypothesis metaphorically comparing various cytokinin forms, enzymes of CK metabolism, and their signalling and transporter functions to the comics superheroes Hulk and Deadpool. Hulk is a powerful but short-lived creation, whilst Deadpool presents a more subtle and enduring force. With this dual framework in mind, this review compares different cytokinin metabolites, and their bio-synthesis, translocation, and sensing to illustrate the different mechanisms behind the two CK strat-egies. This is put together and applied to a plant developmental scale and, beyond plants, to interactions with organisms of other kingdoms, to highlight where future study can benefit the understanding of plant fitness and productivity.
Permanent Link: http://hdl.handle.net/11104/0321244