Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein

SMOLA, Miroslav, GUTTEN, Ondrej, DEJMEK, Milan, KOŽÍŠEK, Milan, EVANGELIDIS, Thomas, TEHRANI, Zahra Aliakbar, NOVOTNÁ, Barbora, NENCKA, Radim, BIRKUŠ, Gabriel, RULÍŠEK, Lubomír, BOUŘA, Evžen. Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angewandte Chemie - International Edition. 2021, 60(18), 10172-10178. ISSN 1433-7851. E-ISSN 1521-3773. Available: doi: 10.1002/anie.202016805.