Number of the records: 1
Translational Research in Serious Human Diseases
- 1.0536630 - ÚŽFG 2021 RIV CZ eng M - Monography Chapter
Vinšová, Johana - Drutovič, Dávid
The role of chromosomal signalling gradients in spindle assembly and chromosome segregation during oocyte meiosis.
Translational Research in Serious Human Diseases. Praha: Academia, 2020 - (Kello, M.; Strnadel, J.; Klempir, J.; Roth, J.; Myslivcová-Fučíková, A.; Hansíková, H.; Kozák, I.), s. 265-271. ISBN 978-80-200-3158-7
R&D Projects: GA MŠMT(CZ) LO1609; GA MŠMT(CZ) LTAUSA17097
Institutional support: RVO:67985904
Keywords : oocyte * spindle * RanGTP
OECD category: Reproductive biology (medical aspects to be 3)
Vertebrate reproduction biology is very specific especially when talking about mammals, including humans. In this short review, we are concerned about the oocyte-specific features of meiotic division. Further, we are describing the function of two chromosomal signalling gradients, RanGTP (guanosine triphosphate-bound Ran)-importin β and chromosomal passenger complex during meiosis in different species, their effect on spindle assembly in oocytes and summarizing the latest speculations about more possible functions.
Permanent Link: http://hdl.handle.net/11104/0314376
Number of the records: 1