Number of the records: 1  

Multiscale Experimental Evaluation of Agarose-Based Semi-Interpenetrating Polymer Network Hydrogels as Materials with Tunable Rheological and Transport Performance

  1. 1.
    SYSNO ASEP0536286
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleMultiscale Experimental Evaluation of Agarose-Based Semi-Interpenetrating Polymer Network Hydrogels as Materials with Tunable Rheological and Transport Performance
    Author(s) Trudičová, M. (CZ)
    Smilek, J. (CZ)
    Kalina, M. (CZ)
    Smilková, M. (CZ)
    Adámková, Kateřina (UPT-D)
    Hrubanová, Kamila (UPT-D) RID, SAI, ORCID
    Krzyžánek, Vladislav (UPT-D) RID, ORCID, SAI
    Sedláček, P. (CZ)
    Number of authors8
    Article number2561
    Source TitlePolymers. - : MDPI
    Roč. 12, č. 11 (2020)
    Number of pages25 s.
    Publication formPrint - P
    Languageeng - English
    CountryCH - Switzerland
    Keywordshydrogels ; semi-interpenetrating polymer networks ; controlled release systems ; rheology ; diffusion ; cryo-scanning electron microscopy
    Subject RIVCD - Macromolecular Chemistry
    OECD categoryPolymer science
    R&D ProjectsGA17-15451S GA ČR - Czech Science Foundation (CSF)
    Method of publishingOpen access
    Institutional supportUPT-D - RVO:68081731
    UT WOS000594401200001
    EID SCOPUS85094821516
    DOI10.3390/polym12112561
    AnnotationThis study introduces an original concept in the development of hydrogel materials for controlled release of charged organic compounds based on semi-interpenetrating polymer networks composed by an inert gel-forming polymer component and interpenetrating linear polyelectrolyte with specific binding affinity towards the carried active compound. As it is experimentally illustrated on the prototype hydrogels prepared from agarose interpenetrated by poly(styrene sulfonate) (PSS) and alginate (ALG), respectively, the main benefit brought by this concept is represented by the ability to tune the mechanical and transport performance of the material independently via manipulating the relative content of the two structural components. A unique analytical methodology is proposed to provide complex insight into composition-structure-performance relationships in the hydrogel material combining methods of analysis on the macroscopic scale, but also in the specific microcosms of the gel network. Rheological analysis has confirmed that the complex modulus of the gels can be adjusted in a wide range by the gelling component (agarose) with negligible effect of the interpenetrating component (PSS or ALG). On the other hand, the content of PSS as low as 0.01 wt.% of the gel resulted in a more than 10-fold decrease of diffusivity of model-charged organic solute (Rhodamine 6G).
    WorkplaceInstitute of Scientific Instruments
    ContactMartina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178
    Year of Publishing2021
    Electronic addresshttps://www.mdpi.com/2073-4360/12/11/2561/htm
Number of the records: 1  

  This site uses cookies to make them easier to browse. Learn more about how we use cookies.