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Studies in Natural Products Chemistry
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SYSNO ASEP 0534978 Document Type M - Monograph Chapter R&D Document Type Monograph Chapter Title Alternative sources of omega-3 polyunsaturated fatty acids Author(s) Řezanka, Tomáš (MBU-M) ORCID
Kolouchová, I. (CZ)
Maťáková, O. (CZ)Source Title Studies in Natural Products Chemistry, Bioactive Natural Products, 67. - Karachi : Elsevier B.V., 2020 / Rahman Atta-ur - ISSN 1572-5995 - ISBN 978-0-12-819483-6 Pages s. 123-160 Number of pages 38 s. Number of pages 527 Publication form Print - P Language eng - English Country PK - Pakistan Keywords omega-3 polyunsaturated fatty acids ; eicosapentaenoic acid ; eicosapentaenoic acid Subject RIV EE - Microbiology, Virology OECD category Microbiology Institutional support MBU-M - RVO:61388971 DOI 10.1016/B978-0-12-819483-6.00004-7 Annotation This chapter describes potential undeveloped microbial sources of omega-3 polyunsaturated fatty acids (ω-3 PUFAs), with a special focus on eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are important components of mammalian (and human) food. These microorganisms of interest are often characterized by the production of PUFAs by type I polyketide synthase (PKS I). Unlike common organisms, from cyanobacteria to higher plants or from protozoa to mammals, in which ω-3 PUFAs are produced by classical biosynthetic pathways, sometimes called aerobic biosynthesis, bacteria and some other microorganisms produce ω-3 PUFAs using a different approach. PKS I uses an acyl carrier protein for hydrocarbon chain synthesis and continues the iterative cycles with the addition of C2 units and double bonds. PKS I has been detected in a number of deep-sea bacteria such as (e.g., Shewanella sp. and Photobacterium sp.) and in dinoflagellates (e.g., Schizochytrium and Thraustochytrium). Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2021 Electronic address https://www.sciencedirect.com/science/article/pii/B9780128194836000047
Number of the records: 1