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RNA Metabolism in Mitochondria
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SYSNO ASEP 0503024 Document Type M - Monograph Chapter R&D Document Type Monograph Chapter Title Mitochondrial RNA Editing and Processing in Diplonemid Protists Author(s) Faktorová, Drahomíra (BC-A) RID, ORCID
Valach, M. (CA)
Kaur, Binnypreet (BC-A) ORCID
Burger, G. (CA)
Lukeš, Julius (BC-A) RID, ORCIDNumber of authors 5 Source Title RNA Metabolism in Mitochondria. - Cham : Springer, Cham, 2018 / Cruz-Reyes J. ; Gray M.W. - ISSN 0933-1891 - ISBN 978-3-319-78189-1 Pages roč. 34 (2018), s. 145-176 Series Nucleic Acids and Molecular Biology Number of pages 32 s. Number of pages 249 Publication form Print - P Language eng - English Country CH - Switzerland Keywords ribosomal-rna ; trypanosoma-brucei ; physarum-polycephalum ; unexpected diversity ; character evolution ; fragmented genes ; euglena-gracilis ; messenger-rnas ; genome ; dna Subject RIV EB - Genetics ; Molecular Biology OECD category Genetics and heredity (medical genetics to be 3) R&D Projects GA15-21974S GA ČR - Czech Science Foundation (CSF) GA16-18699S GA ČR - Czech Science Foundation (CSF) LL1601 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support BC-A - RVO:60077344 UT WOS 000444256400007 DOI 10.1007/978-3-319-78190-7_6 Annotation RNA editing and processing in the mitochondrion of Diplonema papillatum and other diplonemids are arguably the most complex processes of their kind described in any organelle so far. Prior to translation, each transcript has to be accurately trans-spliced from gene fragments encoded on different circular chromosomes. About half of the transcripts are massively edited by several types of substitution editing and addition of blocks of uridines. Comparative analysis of mitochondrial RNA processing among the three euglenozoan groups, diplonemids, kinetoplastids, and euglenids, highlights major differences between these lineages. Diplonemids remain poorly studied, yet they were recently shown to be extremely diverse and abundant in the ocean and hence are rapidly attracting increasing attention. It is therefore important to turn them into genetically tractable organisms, and we report here that they indeed have the potential to become such. Workplace Biology Centre (since 2006) Contact Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Year of Publishing 2019
Number of the records: 1