Nanostructures in Biomedicine: Their Regenerative and toxic properties

0499594 - ÚEM 2019 RIV CZ eng M - Monography Chapter
Švecová, Vlasta - Topinka, Jan
The Relation between Personal Exposure and Outdoor Concentrations of Carcinogenic Polycyclic Aromatic Hydrocarbons during Smog Region, Czech Republic.
Nanostructures in Biomedicine: Their Regenerative and toxic properties. Praha 3: Proxima Tisk, s.r.o., 2018 - (Pamula, E.), s. 62-66. ISBN 978-80-906655-7-6
R&D Projects: GA MŠMT(CZ) EF16_019/0000798
Institutional support: RVO:68378041
Keywords : cytotoxicidy * WST-1 assay * organic extract
OECD category: Public and environmental health

Personal exposure to carcinogenic polycyclic aromatic hydrocarbons (cPAHs) bound to airborne particulate matter ≤ 2.5 µm (PM2.5) in periods of high air pollution (smog episode). Measurements were performed in industrial regions of the Czech Republic: Ostrava, Karvina, Havirov. The city of Prague served as a control. The average personal exposure to benzo[a]pyrene (B[a]P) was highest in Ostrava (17.2 ng/m3), followed by Karvina, Havirov, Radvanice and Bartovice and Prague (14.2, 12.0, 9.3, and 2.8 ng/m3, respectively). We test for association between the personal exposure to cPAHs and various health-related factors extracted from the questionnaires, including life style factors and day-to-day activities. Exposure to outdoor cPAHs, environmental tobacco smoke (ETS), commuting, and time spent indoors (in restaurants, workplace or home) were found to be the main determinants of the personal exposure. Daily cPAHs measurements in highly polluted areas are needed for evaluating the personal exposure and to avoid its underestimation resulting from stationary monitoring.
Permanent Link: http://hdl.handle.net/11104/0293424