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New Membranes with Immobilizing Chiral Selector for Racemic Micture Separation.

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    SYSNO ASEP0494930
    Document TypeC - Proceedings Paper (int. conf.)
    R&D Document TypeThe record was not marked in the RIV
    TitleNew Membranes with Immobilizing Chiral Selector for Racemic Micture Separation.
    Author(s) Gaálová, Jana (UCHP-M) RID, SAI, ORCID
    Cuřínová, Petra (UCHP-M) RID, SAI, ORCID
    Stibor, Ivan (UCHP-M)
    Izák, Pavel (UCHP-M) RID, ORCID, SAI
    Article numberT1 / SL 04
    Source TitleBook of Abstracts. - Prague : Czech Membrane Platform, 2018 - ISBN 978-80-906831-2-9
    Pagess. 47
    Number of pages1 s.
    Publication formOnline - E
    ActionInternational Conference on Membrane Processes
    Event date13.05.2018 - 16.05.2018
    VEvent locationPrague
    CountryCZ - Czech Republic
    Event typeWRD
    Languageeng - English
    CountryCZ - Czech Republic
    Keywordspetraction ; racemic mixture ; chiral selector membrane
    Subject RIVCI - Industrial Chemistry, Chemical Engineering
    OECD categoryChemical process engineering
    R&D ProjectsGA17-00089S GA ČR - Czech Science Foundation (CSF)
    Institutional supportUCHP-M - RVO:67985858
    AnnotationEnantiomers exhibit identical properties in the achiral environment, however, they often differ in effectiveness, pharmacological activity and pharmacokinetic profile since the modules with which they interact in biological systems are also optically active [1,2]. Racemic immobilizing chiral selector is present. Five types of membranes with different amount of chiral selector were used. During the pertraction experiments the membranes were subsequently placed between the feed and receiving phase of the pertraction cell. During pertraction experiments we find out, that kinetics of the pertraction significantly influence the enantiomer resolution what indicated that facilitated transport is employed; while enantioselective sorption activity of the membranes reached up to 100%.
    WorkplaceInstitute of Chemical Process Fundamentals
    ContactEva Jirsová, jirsova@icpf.cas.cz, Tel.: 220 390 227
    Year of Publishing2019
Number of the records: 1  

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