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Mechanical response of the cross-linked pericardial tissue
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SYSNO ASEP 0486663 Document Type C - Proceedings Paper (int. conf.) R&D Document Type The record was not marked in the RIV Title Mechanical response of the cross-linked pericardial tissue Author(s) Gultová, E. (CZ)
Horný, L. (CZ)
Chlup, H. (CZ)
Filová, Elena (FGU-C) RID, ORCID
Staňková, Ľubica (FGU-C) RID, ORCID
Pirk, J. (CZ)
Bačáková, Lucie (FGU-C) RID, ORCID
Žitný, R. (CZ)Source Title Experimental stress analysis 51. - Zürich : Trans Tech Publications, 2014 / Petrenko Alena - ISSN 1660-9336 - ISBN 978-3-03785-977-3 Pages s. 255-258 Number of pages 4 s. Publication form Print - P Action International Scientific Conference on Experimental Stress Analysis /51./ Event date 11.06.2013 - 13.06.2013 VEvent location Litoměřice Country CZ - Czech Republic Event type WRD Language eng - English Country CH - Switzerland Keywords pericardium ; mechanical properties ; cross-linking ; glutaraldehyde ; genipin Subject RIV FA - Cardiovascular Diseases incl. Cardiotharic Surgery R&D Projects NT11270 GA MZd - Ministry of Health (MZ) Institutional support FGU-C - RVO:67985823 UT WOS 000335709900047 EID SCOPUS 84892173426 DOI 10.4028/www.scientific.net/AMM.486.255 Annotation The significance of studying of human pericardial mechanics arises from a wide range of possible applications. For instance, tissue engineers study potential use of a human pericardium in a design of homograft valve bioprosthesis. In cooperation with the Institute of the Physiology of Academy of Sciences of the Czech Republic, human pericardium tissue has been modified by different cross-linking agents. The function and performance of the potential future bioprostheses depends closely on sources material. Thus characterization of the mechanical properties of the human pericardial tissue is an important problem. Several samples of pericardial tissue as well as cross-linked tissue underwent uniaxial loading and unloading. Their nonlinear mechanical response was modeled using hyperelastic theory, assuming incompressible isotropic deformation. Considering future possible tissue application, mechanical properties of the material under stress corresponding to the loading in aortic valve were evaluated. Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2018
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