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Prompt gamma-ray emission for future imaging applications in proton-boron fusion therapy
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SYSNO ASEP 0480147 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Prompt gamma-ray emission for future imaging applications in proton-boron fusion therapy Author(s) Petringa, G. (IT)
Cirrone, G. A. P. (IT)
Caliri, C. (IT)
Cuttone, G. (IT)
Giuffrida, Lorenzo (FZU-D) ORCID
La Rosa, G. (IT)
Manna, R. (IT)
Manti, L. (IT)
Marchese, V. (IT)
Marchetta, C. (IT)
Margarone, Daniele (FZU-D) RID, ORCID
Milluzzo, G. (IT)
Picciotto, A. (IT)
Romano, F. (IT)
Romano, F.P. (IT)
Russo, A.D. (IT)
Russo, G. (IT)
Santonocito, D. (IT)
Scuderi, Valentina (FZU-D) RIDNumber of authors 19 Article number C03059 Source Title Journal of Instrumentation. - : Institute of Physics Publishing - ISSN 1748-0221
Roč. 12, Mar (2017), s. 1-4Number of pages 4 s. Language eng - English Country GB - United Kingdom Keywords instrumentation for particle-beam therapy ; targets ; spallation source targets ; radioisotope production ; neutrino and muon sources Subject RIV BL - Plasma and Gas Discharge Physics OECD category Fluids and plasma physics (including surface physics) R&D Projects EF15_008/0000162 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) LQ1606 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support FZU-D - RVO:68378271 UT WOS 000406997400059 EID SCOPUS 85017478691 DOI 10.1088/1748-0221/12/03/C03059 Annotation Recently, an approach exploiting the proton therapy biological enhancement by using Boron atoms injected inside a tumor, has been proposed [1-3]. Here, the B-11( p,alpha)2 alpha nuclear fusion reaction channel, where three alpha particles are produced with an average energy around 4MeV, is considered [4]. These alphas are able to penetrate the cells nucleus and strongly damage their DNA. In addition, gamma prompts emitted by the proton Boron nuclear reactions can be used for on-line proton beam imaging purposes. Workplace Institute of Physics Contact Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Year of Publishing 2018
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