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Carbonic anhydrase inhibitors and method of their production
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SYSNO ASEP 0471686 Document Type P - Patent R&D Document Type Patent or other outcome protected by special legislation Title Carbonic anhydrase inhibitors and method of their production Author(s) Brynda, Jiří (UOCHB-X) RID, ORCID
Cígler, Petr (UOCHB-X) RID, ORCID
Grüner, Bohumír (UACH-T) RID, SAI, ORCID
Maloy Řezáčová, Pavlína (UOCHB-X) RID, ORCID
Mader, P. (CZ)
Šícha, Václav (UACH-T) RID, ORCID, SAI
Bakardjiev, Mario (UACH-T) SAI, RID
Holub, Josef (UACH-T) SAI, RID, ORCID
Džubák, P. (CZ)
Hajdúch, M. (CZ)Year of issue 2016 Possible third party use of the result A - Pro využití výsledku jiným subjektem je vždy nutné nabytí licence Royalty requested A - Poskytovatel licence požaduje licenční poplatek Patent no. or utility model no. or industrial design no. US9290529 Date of the patent acceptance 22.03.2016 Name of the patent owner Ústav organické chemie a biochemie AV ČR, v. v. i. - Ústav molekulární genetiky AV ČR, v. v. i. - Ústav anorganické chemie AV ČR, v. v. i. - Univerzita Palackého v Olomouci Code of the issuer name US001 - United States Patent and Trademark Office (USPTO) Alexandria Current use A - Pouze udělený (dosud nevyužívaný) patent nebo patent využívaný jeho vlastníkem Language eng - English Keywords cancer enzyme ; inhibition ; carboranes Subject RIV CE - Biochemistry Subject RIV - cooperation Institute of Inorganic Chemistry - Inorganic Chemistry Institutional support UOCHB-X - RVO:61388963 ; UACH-T - RVO:61388980 Annotation Derivatives of boron cluster compounds of general formula I and their pharmaceutically acceptable salts and solvates, and their specific inhibition effect on the enzyme carbonic anhydrase IX, a protein overexpressed in cancer tissues. Methods of synthesis and the use of the novel derivatives. These inhibitors of human carbonic anhydrase IX can be used as active compounds of pharmaceuticals for diagnostics and/or therapy of cancer diseases. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Year of Publishing 2017 Electronic address https://worldwide.espacenet.com/publicationDetails/biblio?CC=US&NR=9290529B2&KC=B2&FT=D&ND=4&date=20160322&DB=&locale=en_EP#
Number of the records: 1