Spatial navigation in virtual reality - from animal models towards schizophrenia Spatial cognition tests based on animal research

0471327 - FGÚ 2017 RIV US eng C - Conference Paper (international conference)
Fajnerová, I. - Rodriquez, M. - Španiel, F. - Horáček, J. - Vlček, Kamil - Levčík, David - Stuchlík, Aleš - Brom, C.
Spatial navigation in virtual reality - from animal models towards schizophrenia Spatial cognition tests based on animal research.
INTERNATIONAL CONFERENCE ON VIRTUAL REHABILITATION PROCEEDINGS. New York: IEEE, 2015, s. 44-50. ISBN 978-1-4799-8984-3.
[International Conference on Virtual Rehabilitation 2015. Valencia (ES), 09.06.2015-12.06.2015]
R&D Projects: GA MZd(CZ) NT13386
Institutional support: RVO:67985823
Keywords : cognitive functions * spatial navigation * schizophrenia * virtual reality environment
Subject RIV: FH - Neurology

In order to demonstrate the deficit of spatial cognition in schizophrenia and to test the validity of pharmacological model, we designed two virtual tasks inspired by previous animal research: the virtual Morris water maze and Carousel maze. Data obtained in a group of schizophrenia patients and matched group of healthy volunteers show cognitive impairment in first episodes of schizophrenia using both, standardized neurocognitive methods and newly-developed virtual tests. The virtual test batteries show different involvement of navigation strategies and different level of impairment in schizophrenia patients. These findings indicate usefulness of these virtual methods in future cognitive remediation.
Permanent Link: http://hdl.handle.net/11104/0268720