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Needleless coaxial electrospinning: A novel approach to mass production of coaxial nanofibers.
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SYSNO ASEP 0469054 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Needleless coaxial electrospinning: A novel approach to mass production of coaxial nanofibers. Author(s) Vysloužilová, L. (CZ)
Buzgo, Matej (UEM-P)
Pokorný, P. (CZ)
Chvojka, J. (CZ)
Míčková, Andrea (UEM-P)
Klusáček Rampichová, Michala (UEM-P) RID, ORCID
Kula, J. (CZ)
Pejchar, K. (CZ)
Bílek, M. (CZ)
Lukáš, D. (CZ)
Amler, Evžen (UEM-P) RIDSource Title International Journal of Pharmaceutics. - : Elsevier - ISSN 0378-5173
Roč. 516, 1-2 (2017), s. 293-300Number of pages 8 s. Language eng - English Country GB - United Kingdom Keywords core-shell nanofibers ; coaxial electrospinning ; needleless electrospinning Subject RIV EB - Genetics ; Molecular Biology OECD category Nano-materials (production and properties) R&D Projects GA15-15697S GA ČR - Czech Science Foundation (CSF) LO1508 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) LO1309 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support UEM-P - RVO:68378041 UT WOS 000390437300032 EID SCOPUS 84997427344 DOI https://doi.org/10.1016/j.ijpharm.2016.11.034 Annotation Herein, we describe a simple spinneret setup for needleless coaxial electrospinning that exceeds the limited production capacity of current approaches. The proposed weir spinneret enables coaxial electrospinning from free liquid surface. This approach leads to the formation of coaxial nanofibers with higher and uniform shell/core ratio, which results in the possibility of better tuning of the degradation rate. The throughput and quality increase favor the broader application of coaxial nanofibers from weir spinnerets as systems for controlled drug delivery in regenerative medicine and tissue engineering. (C) 2016 Elsevier B.V. All rights reserved. Workplace Institute of Experimental Medicine Contact Arzuv Čaryjeva, arzuv.caryjeva@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2018
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