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Congenital Heart Diseases: The Broken Heart. Clinical Features, Human Genetics and Molecular Pathways
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SYSNO ASEP 0460371 Document Type M - Monograph Chapter R&D Document Type Monograph Chapter Title Hemodynamics During Development and Postnatal Life Author(s) Sedmera, David (FGU-C) RID, ORCID, SAI Source Title Congenital Heart Diseases: The Broken Heart. Clinical Features, Human Genetics and Molecular Pathways. - Wien : Springer-Verlag, 2016 / Rickert-Sperling Silke ; Kelly Robert G. ; Driscoll David J. - ISBN 978-3-7091-1882-5 Pages s. 97-107 Number of pages 11 s. Number of pages 765 Publication form Print - P Language eng - English Country AT - Austria Keywords embryo ; heart ; fetal ; blood flow ; growth Subject RIV FA - Cardiovascular Diseases incl. Cardiotharic Surgery R&D Projects GA13-12412S GA ČR - Czech Science Foundation (CSF) GAP302/11/1308 GA ČR - Czech Science Foundation (CSF) Institutional support FGU-C - RVO:67985823 EID SCOPUS 84978357240 DOI https://doi.org/10.1007/978-3-7091-1883-2_9 Annotation Unlike other embryonic organs, the developing heart must support, through its proper function, the developing embryo from time diffusion becomes limiting. Hemodynamics is thus not only a key to remodeling of the developing vasculature but also a powerful stimulus for cardiac growth and differentiation. In this chapter are discussed prenatal models of hemodynamic perturbation that help clarifying the role of blood flow in emryogenesis. Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2017
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