The impact of silica encapsulated cobalt zinc ferrite nanoparticles on DNA, lipids and proteins of rat bone marrow mesenchymal stem cells.

Novotná, Božena; Turnovcová, Karolína; Veverka, Pavel; Rössner ml., Pavel; Bagryantseva, Yana; Herynek, Vít; Zvatora, P.; Vosmanská, M.; Klementová, M.; Syková, Eva; Jendelová, Pavla

doi:https://dx.doi.org/10.3109/17435390.2015.1107144

Number of the records: 1

The impact of silica encapsulated cobalt zinc ferrite nanoparticles on DNA, lipids and proteins of rat bone marrow mesenchymal stem cells.

1.

SYSNO ASEP	0459627
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	The impact of silica encapsulated cobalt zinc ferrite nanoparticles on DNA, lipids and proteins of rat bone marrow mesenchymal stem cells.
Author(s)	Novotná, Božena (UEM-P) Turnovcová, Karolína (UEM-P)_ORCID Veverka, Pavel (FZU-D)_{RID, ORCID} Rössner ml., Pavel (UEM-P)_{RID, ORCID} Bagryantseva, Yana (UEM-P) Herynek, Vít (UEM-P) Zvatora, P. (CZ) Vosmanská, M. (CZ) Klementová, M. (CZ) Syková, Eva (UEM-P)_RID Jendelová, Pavla (UEM-P)_{RID, ORCID}
Source Title	Nanotoxicology. - : Taylor & Francis - ISSN 1743-5390 Roč. 10, č. 6 (2016), s. 662-670
Number of pages	9 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	comet assay ; cytotoxicity ; genotoxicity ; lipid peroxidation
Subject RIV	EB - Genetics ; Molecular Biology
OECD category	Cell biology
R&D Projects	GAP304/12/1370 GA ČR - Czech Science Foundation (CSF)
	LO1309 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	LO1508 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
Method of publishing	Limited access
Institutional support	UEM-P - RVO:68378041 ; FZU-D - RVO:68378271
UT WOS	000379248300003
EID SCOPUS	84947282853
DOI	10.3109/17435390.2015.1107144
Annotation	Cobalt zinc ferrite nanoparticles (Co0.5Zn0.5Fe2O4+γ [CZF-NPs]) encapsulated by amorphous silica we prepared and tested in order to find a safe contrast agent and magnetic label for tracking transplanted cells within an organism using magnetic resonance imaging (MRI). No harmful effects were detected in cells exposed to the low dose of CZF-NPs. Nevertheless, the labeled cells still exhibited an adequate relaxation rate for MRI in repeated experiments and ICP-MS confirmed sufficient magnetic label concentrations inside the cells.
Workplace	Institute of Experimental Medicine
Contact	Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
Year of Publishing	2017
Electronic address	https://www.tandfonline.com/doi/full/10.3109/17435390.2015.1107144

Number of the records: 1