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A Deep Insight Into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera)
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SYSNO ASEP 0451298 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title A Deep Insight Into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera) Author(s) Ribeiro, J.M.C. (US)
Schwarz, Alexandra (BC-A)
Francischetti, I.M.B. (US)Source Title Journal of Medical Entomology. - : Oxford University Press - ISSN 0022-2585
Roč. 52, č. 3 (2015), s. 351-358Number of pages 8 s. Publication form Print - P Language eng - English Country US - United States Keywords Chagas disease ; vector biology ; salivary gland ; transcriptome ; medical entomology Subject RIV FN - Epidemiology, Contagious Diseases ; Clinical Immunology R&D Projects LH12002 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GPP302/11/P798 GA ČR - Czech Science Foundation (CSF) Institutional support BC-A - RVO:60077344 UT WOS 000356720600008 DOI 10.1093/jme/tjv023 Annotation Saliva of blood-sucking arthropods contains a complex cocktail of pharmacologically active compounds that assists feeding by counteracting their hosts' hemostatic and inflammatory reactions. Panstrongylus megistus (Burmeister) is an important vector of Chagas disease in South America, but despite its importance there is only one salivary protein sequence publicly deposited in GenBank. In the present work, we used Illumina technology to disclose and publicly deposit 3,703 coding sequences obtained from the assembly of >70 million reads. These sequences should assist proteomic experiments aimed at identifying pharmacologically active proteins and immunological markers of vector exposure. Workplace Biology Centre (since 2006) Contact Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Year of Publishing 2016
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