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Bad and Bid - potential background players in preneoplastic to neoplastic shift in human endometrium
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SYSNO ASEP 0439233 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Bad and Bid - potential background players in preneoplastic to neoplastic shift in human endometrium Author(s) Driak, D. (CZ)
Dvorská, M. (CZ)
Bolehovská, P. (CZ)
Švandová, Iva (FGU-C)
Novotný, J. (CZ)
Halaška, M. (CZ)Source Title Neoplasma - ISSN 0028-2685
Roč. 61, č. 4 (2014), s. 411-415Number of pages 5 s. Language eng - English Country SK - Slovakia Keywords Bad ; Bid ; cancerogenesis ; human endometrium Subject RIV CE - Biochemistry R&D Projects GAP207/12/0919 GA ČR - Czech Science Foundation (CSF) Institutional support FGU-C - RVO:67985823 UT WOS 000342881700005 EID SCOPUS 84904394600 DOI https://doi.org/10.4149/neo_2014_050 Annotation In this study, the levels of Bid and Bad were measured using SDS-PAGE and Western blotting with specific antibodies, with the aim to analyse expression of Bid and Bad proteins in normal (NE), hyperplastic (HE) and cancerous (CE) endometrium. We demonstrated that Bid levels in CE reached only 47% and 50% of this observed in NE and HE. Conversely, Bad le vels in HE reached only 40% and 36% of this observed in NE and CE, respectively. We detected no significant changes of Bid levels between HE and NE, and levels of Bad protein were not different between CE and NE Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2015
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