Number of the records: 1
Addition of ETA receptor blockade increases renoprotection provided by renin-angiotensin system blockade in 5/6 nephrectomized Ren-2 transgenic rats
- 1.0439090 - FGÚ 2015 RIV GB eng J - Journal Article
Čertíková - Chábová, V. - Vernerová, Z. - Kujal, P. - Husková, Z. - Škaroupková, P. - Tesař, V. - Kramer, H. J. - Kompanowska - Jezierska, E. - Walkowska, A. - Sadowski, J. - Červenka, L. - Vaněčková, Ivana
Addition of ETA receptor blockade increases renoprotection provided by renin-angiotensin system blockade in 5/6 nephrectomized Ren-2 transgenic rats.
Life Sciences. Roč. 118, č. 2 (2014), s. 297-305. ISSN 0024-3205. E-ISSN 1879-0631
R&D Projects: GA ČR(CZ) GAP304/12/0259
Institutional support: RVO:67985823
Keywords : renal failure * 5/6 nephrectomy * renin-angiotensin * endothelin * survival
Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery
Impact factor: 2.702, year: 2014
In a model of chronic renal failure induced by 5/6 nephrectomy, we studied the effect of long-term (10 months) of combined renin-angiotensin (RAS) and endothelin (ET) receptor blockades. The addition of ET receptor blockade to classical RAS blockade had substantial effects on the survival of animals, probably due to the regressed renal damage
Permanent Link: http://hdl.handle.net/11104/0242412
Number of the records: 1