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Adipose tissue-related proteins locally associated with resolution of inflammation in obese mice

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    0428947 - FGÚ 2015 RIV GB eng J - Journal Article
    Jílková, Zuzana - Hensler, Michal - Medříková, Daša - Janovská, Petra - Horáková, Olga - Rossmeisl, Martin - Flachs, Pavel - Sell, H. - Eckel, J. - Kopecký, Jan
    Adipose tissue-related proteins locally associated with resolution of inflammation in obese mice.
    International Journal of Obesity. Roč. 38, č. 2 (2014), s. 216-223. ISSN 0307-0565. E-ISSN 1476-5497
    R&D Projects: GA MZd(CZ) NT13763; GA MŠMT(CZ) 7E12073
    Institutional support: RVO:67985823
    Keywords : eicosapentaenoic acid * docosahexaenoic acid * inflammation * obesity
    Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition
    Impact factor: 5.004, year: 2014

    The short-term dietary combined intervention (rosiglitazone and concentrate n-3 long-chain PUFA, namely eicosapentaenoic acid and docosahexaenoic acid) exerted additive effect in the amelioration of WAT inflammation in obese mice, namely in the epididymal fat, even in the absence of any changes in either adipocyte volume or fat mass. The combined intervention elicited hypolipidaemic effect and induced adiponectin. We identified several adipose tissue-related proteins, which are involved in resolution of low-grade inflammation and remodeling of WAT
    Permanent Link: http://hdl.handle.net/11104/0234169

     
     
Number of the records: 1  

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