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Ultrasound Perfusion Analysis Combining Bolus-Tracking and Burst-Replenishment
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SYSNO ASEP 0421688 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Ultrasound Perfusion Analysis Combining Bolus-Tracking and Burst-Replenishment Author(s) Jiřík, Radovan (UPT-D) RID, ORCID, SAI
Nylund, K. (NO)
Gilja, O.H. (NO)
Mézl, M. (CZ)
Harabis, V. (CZ)
Kolář, R. (CZ)
Standara, M. (CZ)
Taxt, T. (NO)Number of authors 8 Source Title IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control. - : Institute of Electrical and Electronics Engineers - ISSN 0885-3010
Roč. 60, č. 2 (2013), s. 310-319Number of pages 10 s. Publication form Print - P Language eng - English Country US - United States Keywords contrast-enhaced ultrasound ; myocardial blood-flow ; cerebral perfusion Subject RIV FS - Medical Facilities ; Equipment R&D Projects GAP102/12/2380 GA ČR - Czech Science Foundation (CSF) ED0017/01/01 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support UPT-D - RVO:68081731 UT WOS 000314370100006 EID SCOPUS 84873842235 DOI https://doi.org/10.1109/TUFFC.2013.2567 Annotation A new signal model and processing method for quantitative ultrasound perfusion analysis is presented, called bolus-and-burst. The method has the potential to provide absolute values of blood flow, blood volume, and mean transit time. Furthermore, it provides an estimate of the local arterial input function which characterizes the arterial tree, allowing accurate estimation of the bolus arrival time. The method combines two approaches to ultrasound perfusion analysis: bolus-tracking and burst-replenishment. A pharmacokinetic model based on the concept of arterial input functions and tissue residue functions is used to model both the bolus and replenishment parts of the recording. The pharmacokinetic model is fitted to the data using blind deconvolution. A preliminary assessment of the new perfusion-analysis method is presented on clinical recordings. Workplace Institute of Scientific Instruments Contact Martina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178 Year of Publishing 2014
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