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Neuroglia
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SYSNO ASEP 0388979 Document Type M - Monograph Chapter R&D Document Type Monograph Chapter Title Control of the extracellular ionic environment and volume Author(s) Syková, Eva (UEM-P) RID Source Title Neuroglia, Third Edition. - New York : Oxford University Press, 2013 / Kettenmann, H. - Ransom, B. R. - ISBN 978-0-19-979459-1 Pages s. 430-442 Number of pages 13 s. Number of pages 930 Publication form Print - P Language eng - English Country US - United States Keywords neurons ; extracellular space ; central nervous system Subject RIV FH - Neurology R&D Projects GA309/09/1597 GA ČR - Czech Science Foundation (CSF) Institutional support UEM-P - RVO:68378041 DOI 10.1093/med/9780199794591.003.0034 Annotation It is evident that glial cells play an important role in different brain functions. Voltage- and ligand-activated channels and a number of transport mechanisms on the glial membrane allow for the maintenance of ionic and volume homeostasis, which in turn affect neuronal function. The production of extracellular matrix molecules by activated astrocytes further hinders already impaired diffusion and contributes to an increase in tortuosity. Astrocytes can thus be viewed as active elements in signal transmission as they affect both synaptic as well as extrasynaptic volume transmission. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2014
Number of the records: 1