Number of the records: 1
Virucidal Nanofiber Textiles Based on Photosensitized Production of Singlet Oxygen
- 1.0384371 - ÚFCH JH 2013 RIV US eng J - Journal Article
Lhotáková, Y. - Plištil, L. - Morávková, A. - Kubát, Pavel - Lang, Kamil - Forstová, J. - Mosinger, J.
Virucidal Nanofiber Textiles Based on Photosensitized Production of Singlet Oxygen.
PLoS ONE. Roč. 7, č. 11 (2012), e49226. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR GAP208/10/1678
Institutional support: RVO:61388955 ; RVO:61388980
Keywords : photosynthesis * biomaterials * nanofiber textiles
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 3.730, year: 2012
Novel biomaterials based on hydrophilic polycaprolactone and polyurethane (Tecophilic®) nanofibers with an encapsulated 5,10,5,20-tetraphenylporphyrin photosensitizer were prepared by electrospinning. The doped nanofiber textiles efficiently photo-generate O2(1Δg), which oxidize external chemical and biological substrates/targets. Strong photo-virucidal effects toward non-enveloped polyomaviruses and enveloped baculoviruses were observed on the surface of these textiles. The photo-virucidal effect was confirmed by a decrease in virus infectivity. In contrast, no virucidal effect was detected in the absence of light and/or the encapsulated photosensitizer.
Permanent Link: http://hdl.handle.net/11104/0215307
Number of the records: 1