Synthesis of N-substituted a,a-difluoro-b-aminophosphonates by addition of diethyl lithiodifluoromethylphosphonate to imines

Number of the records: 1

1.

SYSNO ASEP	0379965
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Synthesis of N-substituted a,a-difluoro-b-aminophosphonates by addition of diethyl lithiodifluoromethylphosphonate to imines
Author(s)	Cherkupally, Prabhakar (UOCHB-X) Beier, Petr (UOCHB-X)_{RID, ORCID}
Number of authors	2
Source Title	Journal of Fluorine Chemistry. - : Elsevier - ISSN 0022-1139 Roč. 141, Sep (2012), s. 76-82
Number of pages	7 s.
Language	eng - English
Country	CH - Switzerland
Keywords	nucleophilic addition ; difluorophosphonate ; aminophosphonate ; imines
Subject RIV	CC - Organic Chemistry
R&D Projects	GP203/08/P310 GA ČR - Czech Science Foundation (CSF)
Institutional support	UOCHB-X - RVO:61388963
UT WOS	000308120100012
DOI	https://doi.org/10.1016/j.jfluchem.2012.06.004
Annotation	Addition of diethyl lithiodifluoromethylphosphonate to N-substituted imines provides N-substituted alpha,alpha-difluoro-beta-aminophosphonates. N-Alkyl, aryl, or Boc substituted aldimines give good to high yields in these reactions, while in ketimine series, only activated N-(2,2,2-trifluoro-1-phenylethylidene)aniline showed high reactivity.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418
Year of Publishing	2013

Number of the records: 1