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Polymeric micelles with doxorubicin bound through hydrazon bond - A new promising antitumor drug delivery system
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SYSNO ASEP 0375205 Document Type A - Abstract R&D Document Type Není vybrán druh dokumentu Title Polymeric micelles with doxorubicin bound through hydrazon bond - A new promising antitumor drug delivery system Author(s) Větvička, David (MBU-M)
Hovorka, Ondřej (MBU-M)
Hrubý, Martin (UMCH-V) RID, ORCID
Mrkvan, Tomáš (MBU-M)
Ulbrich, Karel (UMCH-V) RID
Říhová, Blanka (MBU-M) RIDSource Title TUMOR BIOLOGY. - BASEL : KARGER, 2007 - ISSN 1010-4283
-, -, s. 88-88Number of pages 1 s. Action Meeting of the International Society for Oncodevelopmental Biology and Medicine, ISOBM 2007 /35./ Event date 15.09.2007-19.09.2007 VEvent location Prague Country CZ - Czech Republic Event type WRD Language eng - English Country CH - Switzerland Keywords doxorubicin ; polymeric micelles ; drug Subject RIV EC - Immunology R&D Projects KAN200200651 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z50200510 - MBU-M (2005-2011) AV0Z40500505 - UMCH-V (2005-2011) Annotation The work deals of polymeric micelles with doxorubicin bound through hydrazon bond- a new promising antitumour drug delivery system. One of the promising approaches in the therapy of ulcerative colitis is administration of butyrate, an energy source for colonocytes, into the lumen of the colon. This study investigates the effect of butyrate producing bakterium Clostridium tyrobutyricum on dextran sodium sulphate (DSS)-induced colitis in mice. Immunocompetent BALB/c and immunodeficient severe combined immunodeficiency (SCID) mice reared in specific-pathogen-free (SPF) conditions were treated intrarectally with C. tyrobutyricum 1 week prior to the induction of DSS colitis and during oral DSS treatment. Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2012
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