N9-substituted derivatives of kinetin: Effective anti-senescence agents

Mik, V.; Szüčová, Lucie; Šmehilová, M.; Zatloukal, Marek; Doležal, Karel; Nisler, Jaroslav; Grúz, Jiří; Galuszka, Petr; Strnad, Miroslav; Spíchal, Lukáš

doi:https://dx.doi.org/10.1016/j.phytochem.2011.02.002

Number of the records: 1

N9-substituted derivatives of kinetin: Effective anti-senescence agents

1.

SYSNO ASEP	0368599
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	N9-substituted derivatives of kinetin: Effective anti-senescence agents
Author(s)	Mik, V. (CZ) Szüčová, Lucie (UEB-Q)_{RID, ORCID} Šmehilová, M. (CZ) Zatloukal, Marek (UEB-Q)_ORCID Doležal, Karel (UEB-Q)_{RID, ORCID} Nisler, Jaroslav (UEB-Q)_{RID, ORCID} Grúz, Jiří (UEB-Q)_{RID, ORCID} Galuszka, Petr (UEB-Q) Strnad, Miroslav (UEB-Q)_{RID, ORCID} Spíchal, Lukáš (UEB-Q)_{RID, ORCID}
Number of authors	10
Source Title	Phytochemistry. - : Elsevier - ISSN 0031-9422 Roč. 72, č. 8 (2011), s. 821-831
Number of pages	11 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	Cytokinin derivatives ; Synthesis ; Cytokinin activity ; Senescence ; Membrane damage
Subject RIV	EF - Botanics
R&D Projects	GA522/09/1576 GA ČR - Czech Science Foundation (CSF)
	ED0007/01/01 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	LC06034 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	GA301/08/1649 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z50380511 - UEB-Q (2005-2011)
UT WOS	000290505500020
DOI	10.1016/j.phytochem.2011.02.002
Annotation	The first isolated cytokinin, 6-furfurylaminopurine (kinetin or Kin), was identified almost 55 years ago. Its biological effects on plant cells and tissues include influences on such processes as gene expression, cell cycle, chloroplast development, chlorophyll biosynthesis, stimulation of vascular development, delay of senescence, and mobilization of nutrients. In the present study we prepared a series of eight N9-substituted Kin derivatives, and characterized them with available physicochemical methods such as Cl+ mass spectrometry and (1)H NMR spectroscopy. All compounds were tested in three classical cytokinin bioassays: a tobacco callus assay, an Amaranthus assay, and a senescence assay with excised wheat leaves. The ability of the compounds to interact with Arabidopsis cytokinin receptors CRE1/AHK4 and AHK3 was tested in a bacterial receptor assay.
Workplace	Institute of Experimental Botany
Contact	David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469
Year of Publishing	2012

Number of the records: 1