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On-line, real time monitoring of exhaled trace gases by SIFT-MS in the perioperative setting: a feasibility study
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SYSNO ASEP 0363284 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title On-line, real time monitoring of exhaled trace gases by SIFT-MS in the perioperative setting: a feasibility study Author(s) Boshier, P. R. (GB)
Cushnir, J. R. (GB)
Mistry, V. (GB)
Knaggs, A. (GB)
Španěl, Patrik (UFCH-W) RID, ORCID
Smith, D. (GB)
Hanna, G. B. (GB)Source Title Analyst. - : Royal Society of Chemistry - ISSN 0003-2654
Roč. 136, č. 16 (2011), s. 3233-3237Number of pages 5 s. Language eng - English Country GB - United Kingdom Keywords SIFT-MS ; breath analysis Subject RIV CF - Physical ; Theoretical Chemistry CEZ AV0Z40400503 - UFCH-W (2005-2011) UT WOS 000293085000002 DOI 10.1039/C1AN15356K Annotation A study is described of the first on line, real time analyses of the exhaled breath of five anaesthetized patients during the complete perioperative periods of laparoscopic surgery. These breath analyses were achieved using a selected ion flow tube, SIFT-MS, instrument, located in the operating theatre at an acceptable distance from the operating table, and coupled to the endotracheal tube in the ventilation circuit via a 5 metre long capillary tube. Thus, inhalation/exhalation breathing cycles, set to be at a frequency of 10 per minute, were sampled continuously for water vapour, the metabolites acetone and isoprene and the propofol used to induce anaesthesia for each operating period that ranged from 20 min (shortest) to 80 min (longest). Whilst there was some loss of water vapour along the long sampling line, the concentrations of the other trace compounds were not diminished. Workplace J. Heyrovsky Institute of Physical Chemistry Contact Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196 Year of Publishing 2012
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