Preparation, spectral, thermal, and biological properties of zinc(II) 4-chloro- and 5-chlorosalicylate complexes with methyl 3-pyridylcarbamate and phenazone

0346660 - ÚMCH 2011 RIV SK eng J - Journal Article
Bujdošová, Z. - Gyoryova, K. - Hudecová, D. - Kovářová, Jana - Halás, L.
Preparation, spectral, thermal, and biological properties of zinc(II) 4-chloro- and 5-chlorosalicylate complexes with methyl 3-pyridylcarbamate and phenazone.
Chemical Papers. Roč. 64, č. 5 (2010), s. 584-591. ISSN 0366-6352
Institutional research plan: CEZ:AV0Z40500505
Keywords : zinc(II) chlorosalicylate * methyl 3-pyridylcarbamate * phenazone * thermal stability * biological properties
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 0.754, year: 2010

New zinc(II) 4-chloro- and 5-chlorosalicylate complex compounds of the general formula ((4- or 5-Cl)C6H3(2-OH)COO)2Zn · L n (where L = methyl 3-pyridylcarbamate, phenazone; n = 2, 4) were prepared and characterized by elemental analysis, thermal analysis (TG/DTG, DTA), and IR spectroscopy. During thermal decomposition, mpc, phen, chlorosalicylic acid, chlorophenol, carbon dioxide, and carbon monoxide were released. Volatile products of the thermal decomposition were confirmed by mass spectrometry. The final solid product of the thermal decomposition up to 700°C was zinc oxide or metallic zinc. Antimicrobial activity of the compounds prepared was tested against various strains of bacteria, yeasts and filamentous fungi. The highest antimicrobial effect was determined against the G+ bacteria S. aureus.
Permanent Link: http://hdl.handle.net/11104/0005993