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Role of the Transmembrane Potential in the Membrane Proton Leak
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SYSNO ASEP 0345906 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Role of the Transmembrane Potential in the Membrane Proton Leak Author(s) Ruprecht, A. (AT)
Sokolenko, E. A. (AT)
Beck, V. (DE)
Ninnemann, O. (DE)
Jabůrek, Martin (FGU-C) ORCID, RID
Trimbuch, T. (DE)
Klishin, S. S. (RU)
Ježek, Petr (FGU-C) RID, ORCID
Skulachev, V. P. (RU)
Pohl, E. E. (DE)Source Title Biophysical Journal. - : Cell Press - ISSN 0006-3495
Roč. 98, č. 8 (2010), s. 1503-1511Number of pages 9 s. Language eng - English Country US - United States Keywords proton leak ; membrane potential ; uncoupling proteins Subject RIV BO - Biophysics R&D Projects ME09018 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GA303/07/0105 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000276939800016 DOI 10.1016/j.bpj.2009.12.4301 Annotation This study investigates the role of transmembrane potential using planar lipid membranes reconstituted with purified uncoupling proteins (UCPs) and/or unsaturated fatty acids. We show that high membrane potential significantly promotes the protonophoric function of UCPs in the presence of fatty acids Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2011
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