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Inactivation of the left auditory cortex impairs temporal discrimination in the rat
- 1.0345711 - ÚEM 2011 RIV NL eng J - Journal Article
Rybalko, Natalia - Šuta, Daniel - Popelář, Jiří - Syka, Josef
Inactivation of the left auditory cortex impairs temporal discrimination in the rat.
Behavioural Brain Research. Roč. 209, č. 1 (2010), s. 123-130. ISSN 0166-4328. E-ISSN 1872-7549
R&D Projects: GA ČR GA309/07/1336; GA MŠMT(CZ) LC554
Institutional research plan: CEZ:AV0Z50390512
Keywords : auditory cortex * temporal discrimination * hemispheric lateralization
Subject RIV: FH - Neurology
Impact factor: 3.393, year: 2010
http://arl-repository.lib.cas.cz/uloziste_av/UEM-P/cav_un_epca-0345711_01.pdf
The ability of rats to detect or discriminate a series of gaps in continuous noise under conditions of unilateral or bilateral reversible inactivation of the auditory cortex (AC) is studied with the aim to explore the hemispheric lateralization of acoustical signal processing in non-human mammals. The results showed that muscimol-induced reversible inactivation of the left AC suppresses the ability of rats to discriminate between acoustical stimuli of different temporal parameters, whereas inactivation of the right AC results in no change or only a mild decrease in discrimination ability. Our findings demonstrate that, similarly as in humans, the left AC in the rat plays the dominant role in temporal discrimination.
Permanent Link: http://hdl.handle.net/11104/0186916
Number of the records: 1