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On the role of the cis Hoogsteen:sugar-edge family of base pairs in platforms and triplets-quantum chemical insights into RNA structural biology

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    0344071 - BFÚ 2011 RIV US eng J - Journal Article
    Sharma, P. - Šponer, Judit E. - Šponer, Jiří - Sharma, S. - Bhattacharyya, D. - Mitra, A.
    On the role of the cis Hoogsteen:sugar-edge family of base pairs in platforms and triplets-quantum chemical insights into RNA structural biology.
    Journal of Physical Chemistry B. Roč. 114, č. 9 (2010), s. 3307-3320. ISSN 1520-6106. E-ISSN 1520-5207
    R&D Projects: GA MŠMT(CZ) LC06030; GA AV ČR(CZ) IAA400040802; GA ČR(CZ) GA203/09/1476
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : quantum chemistry * base pairs * cis Hoogsteen/Sugar edge
    Subject RIV: BO - Biophysics
    Impact factor: 3.603, year: 2010
    DOI: https://doi.org/10.1021/jp910226e

    Base pairs belonging to the cis Hoogsteen/sugar-edge (H:S) family play important structural roles in folded RNA molecules. We report results of analysis of 30 representative examples spanning 16 possible base pair combinations. The study, involving alternative classification of base pairs and triplets, provides insights into intrinsic properties of these base pairs and their possible structural and functional roles.

    Permanent Link: http://hdl.handle.net/11104/0005935

     
     
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