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Neural Stem/Progenitor Cells Derived from the Embryonic Dorsal Telencephalon of D6/GFP Mice Differentiate Primarily into Neurons After Transplantation into a Cortical Lesion

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    SYSNO ASEP0343344
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleNeural Stem/Progenitor Cells Derived from the Embryonic Dorsal Telencephalon of D6/GFP Mice Differentiate Primarily into Neurons After Transplantation into a Cortical Lesion
    Author(s) Prajerová, Iva (UEM-P)
    Honsa, Pavel (UEM-P)
    Chvátal, Alexandr (UEM-P) RID
    Anděrová, Miroslava (UEM-P) RID, ORCID
    Source TitleCellular and Molecular Neurobiology. - : Springer - ISSN 0272-4340
    Roč. 30, č. 2 (2010), s. 199-218
    Number of pages20 s.
    Languageeng - English
    CountryUS - United States
    Keywordsischemia ; ion channels ; injury and repair
    Subject RIVFH - Neurology
    R&D ProjectsGA305/09/0717 GA ČR - Czech Science Foundation (CSF)
    LC554 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
    CEZAV0Z50390512 - UEM-P (2005-2011)
    UT WOS000275704800005
    EID SCOPUS77952093430
    DOI10.1007/s10571-009-9443-x
    AnnotationD6 is a promoter/enhancer of the mDach1 gene that is involved in the development of the neocortex and hippocampus. Our results indicate that after transplantation into the site of a photochemical lesion, D6/GFP-derived NSPCs survive and differentiate into neurons, and their membrane properties are comparable to those transplanted into the non-injured cortex.
    WorkplaceInstitute of Experimental Medicine
    ContactLenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
    Year of Publishing2011
Number of the records: 1  

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