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Mechanisms participating in oxidative damage of isolated rat hepatocytes
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SYSNO ASEP 0338637 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Mechanisms participating in oxidative damage of isolated rat hepatocytes Author(s) Červinková, Z. (CZ)
Křiváková, P. (CZ)
Lábajová, A. (CZ)
Roušar, T. (CZ)
Lotková, H. (CZ)
Kučera, O. (CZ)
Endlicher, R. (CZ)
Červinka, M. (CZ)
Drahota, Zdeněk (FGU-C) RID, ORCIDSource Title Archives of Toxicology - ISSN 0340-5761
Roč. 83, č. 4 (2009), s. 363-372Number of pages 10 s. Language eng - English Country DE - Germany Keywords hepatocytes ; oxidative damage ; mitochondrial enzymes Subject RIV CE - Biochemistry R&D Projects GA303/06/1261 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000264883800009 DOI 10.1007/s00204-008-0385-8 Annotation It was evaluated concentration dependence and time course of the oxidative damage of cytoplasmic membrane and mitochondrial structure and function. It was found that most sensitive indicators of peroxidative damage are changes of mitochondrial membrane potential and oxidation of NADH-dependent substrates Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2010
Number of the records: 1