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Comparison of cell death-inducing effect of novel taxane SB-T-1216 and paclitaxel in breast cancer cells
- 1.0333896 - ÚMG 2010 RIV GR eng J - Journal Article
Kovář, J. - Ehrlichová, M. - Šmejkalová, Barbora - Zanardi, I. - Ojima, I. - Gut, I.
Comparison of cell death-inducing effect of novel taxane SB-T-1216 and paclitaxel in breast cancer cells.
Anticancer Research. Roč. 29, č. 8 (2009), s. 2951-2960. ISSN 0250-7005. E-ISSN 1791-7530
R&D Projects: GA ČR(CZ) GD204/05/H023
Grant - others:GA MZd(CZ) NR9426; GA ČR(CZ) GA301/09/0362
Institutional research plan: CEZ:AV0Z50520514
Keywords : Cell death * taxane SB-T-1216 * paclitaxel
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 1.428, year: 2009
Cell death induced by both paclitaxel and novel taxane SB-T-1216 in breast cancer cells is associated with caspase activation and with the formation of interphase microtubule bundles. Novel taxane SB-T-1216, but not paclitaxel, seems to be capable of inducing cell death without the accumulation of cells in the G(2)/M phase.
Permanent Link: http://hdl.handle.net/11104/0178771
Number of the records: 1