Mechanical properties of artery-artery connection based upon transglutaminase cross-linked gelatin

Kronek, J.; Žitný, R.; Horný, L.; Chlup, Hynek; Beran, M.

Number of the records: 1

Mechanical properties of artery-artery connection based upon transglutaminase cross-linked gelatin

1.

SYSNO ASEP	0333223
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Ostatní články
Title	Mechanical properties of artery-artery connection based upon transglutaminase cross-linked gelatin
Author(s)	Kronek, J. (CZ) Žitný, R. (CZ) Horný, L. (CZ) Chlup, Hynek (UT-L) Beran, M. (CZ)
Source Title	Metalurgija - ISSN 0543-5846 Roč. 48, č. 3 (2009), s. 153-137
Number of pages	5 s.
Language	eng - English
Country	HR - Croatia
Keywords	biocompatible glue ; transglutaminase ; tensile tests
Subject RIV	BO - Biophysics
R&D Projects	GA106/08/0557 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z20760514 - UT-L (2005-2011)
Annotation	The possibility of surgical repairing of blood vessels by biocompatible adhesive represents an alternative to the conventional sewing techniques. The aim of our study was to evaluate mechanical properties of arteries glued by a cross linked gelatin. Series of quasistatic uniaxial tensile tests of two overlapping arterial strips bonded by the two component glue (gelatin linked by the enzyme transglutaminase) was carried out. The 3D digital image correlation system gave local deformations, and thus the mutual slipping of the bonded strips could be evaluated. The effect of TGA and gelatin concentrations were estimated on the basis of observed data. Recorded maximum stresses were rather small (only tens of kPa). However, cross-linking activity on contact surfaces was proved histologically.
Workplace	Institute of Thermomechanics
Contact	Marie Kajprová, kajprova@it.cas.cz, Tel.: 266 053 154 ; Jana Lahovská, jaja@it.cas.cz, Tel.: 266 053 823
Year of Publishing	2010

Number of the records: 1