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Ex situ voltammetry and chronopotentiometry of doxorubicin at a pyrolytic graphite electrode: Redox and catalytic properties and analytical applications
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SYSNO ASEP 0331446 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Ex situ voltammetry and chronopotentiometry of doxorubicin at a pyrolytic graphite electrode: Redox and catalytic properties and analytical applications Title Ex situ voltametrie a chronopotenciometrie doxorubicinu na elektrodě z pyrolitického grafitu: Oxidačně-redukční a katalytické vlastnosti a analytické aplikace Author(s) Vacek, Jan (BFU-R)
Havran, Luděk (BFU-R) RID, ORCID
Fojta, Miroslav (BFU-R) RID, ORCIDNumber of authors 3 Source Title Electroanalysis. - : Wiley - ISSN 1040-0397
Roč. 21, č. 19 (2009), s. 2139-2144Number of pages 6 s. Language eng - English Country DE - Germany Keywords doxorubicin ; pyrolytic graphite electrode ; chronopotentiometry Subject RIV BO - Biophysics R&D Projects GA203/07/1195 GA ČR - Czech Science Foundation (CSF) LC06035 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) 1QS500040581 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) UT WOS 000270771000008 DOI 10.1002/elan.200904646 Annotation Ex situ electrochemical techniques in connection with PGE have been applied to the study of redox and catalytic properties of doxorubicin (DOX). Voltammetry and chronopotentiometry were used to follow reversible reduction of DOX quinone moiety around -0.5 V and its coupling to catalytic oxygen reduction. The catalytic signal of DOX was used for monitoring of interaction of DOX with DNA. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2010
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