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New hydrophilic HPMA-based polymers for bioreversible shielding of gene delivery vectors
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SYSNO ASEP 0328284 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title New hydrophilic HPMA-based polymers for bioreversible shielding of gene delivery vectors Author(s) Laga, Richard (UMCH-V) RID, ORCID
Koňák, Čestmír (UMCH-V) RID
Šubr, Vladimír (UMCH-V) RID, ORCID
Ulbrich, Karel (UMCH-V) RIDSource Title Macromolecular Chemistry and Physics. - : Wiley - ISSN 1022-1352
Roč. 210, 13-14 (2009), s. 1138-1148Number of pages 11 s. Language eng - English Country DE - Germany Keywords N-(2-hydroxypropyl)methacrylamide copolymers ; polyelectrolyte complexes ; latex nanoparticles Subject RIV CD - Macromolecular Chemistry R&D Projects KAN200200651 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) GA202/09/2078 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z40500505 - UMCH-V (2005-2011) UT WOS 000268687200009 DOI 10.1002/macp.200900078 Annotation New, hydrophilic polymers and copolymers based on HPMA, carrying reactive thiazolidine-2-thione groups either situated at the polymer chain end or randomly distributed along the chains bound to the polymer backbone via spacers containing reductively degradable disulfide linkages, have been developed for an efficient and intracellularly removable coating of gene-delivery vectors. Workplace Institute of Macromolecular Chemistry Contact Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Year of Publishing 2010
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