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DNA adducts of antitumor cisplatin preclude telomeric sequences from forming G quadruplexes
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SYSNO ASEP 0328255 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title DNA adducts of antitumor cisplatin preclude telomeric sequences from forming G quadruplexes Title DNA adukty tvořené protinádorově účinnou cisplatinou zabraňují telomerním sekvencím tvořit G quadruplexy Author(s) Heringová, Pavla (BFU-R)
Kašpárková, Jana (BFU-R) RID, ORCID
Brabec, Viktor (BFU-R) RID, ORCIDSource Title Journal of Biological Inorganic Chemistry. - : Springer - ISSN 0949-8257
Roč. 14, č. 6 (2009), s. 959-968Number of pages 10 s. Language eng - English Country DE - Germany Keywords cisplatin ; DNA quadruplex ; telomere Subject RIV BO - Biophysics R&D Projects NR8562 GA MZd - Ministry of Health (MZ) LC06030 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) ME08017 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) OC08003 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) 1QS500040581 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) KAN200200651 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) IAA400040803 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) UT WOS 000268428900016 DOI 10.1007/s00775-009-0508-6 Annotation We studied the effect of antitumor cisplatin and inefficient transplatin on the structure and stability of G quadruplexes formed by the model human telomere sequence 5'-GGG(TTAGGG)3-3' using circular dichroism, UV-monitored thermal denaturation, and gel electrophoresis. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2010
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