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The crystal structure of the secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A
- 1.0327522 - ÚOCHB 2010 RIV US eng J - Journal Article
Dostál, Jiří - Brynda, Jiří - Hrušková-Heidingsfeldová, Olga - Sieglová, Irena - Pichová, Iva - Řezáčová, Pavlína
The crystal structure of the secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A.
Journal of Structural Biology. Roč. 167, č. 2 (2009), s. 145-152. ISSN 1047-8477. E-ISSN 1095-8657
R&D Projects: GA MŠMT(CZ) LC531
Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50520514
Keywords : aspartic protease * Candida parapsilosis * crystal structure
Subject RIV: CE - Biochemistry
Impact factor: 3.673, year: 2009
We report three-dimensional crystal structure of Sapp1p from C. parapsilosis in complex with pepstatin A, the classical inhibitor of aspartic proteinases. The structure of Sapp1p was determined from protein isolated from its natural source and represents the first structure of Sap from C. parapsilosis.
Permanent Link: http://hdl.handle.net/11104/0174314
Number of the records: 1