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Nitric oxide signaling pathways
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SYSNO ASEP 0324221 Document Type M - Monograph Chapter R&D Document Type Monograph Chapter Title Expression and subcellular redistribution of proteinkinase C isoforms in chronically hypoxic rat heart: effects of inhibitors Title Exprese a subcelulární distribuce izoforem protein kinázy C v chronicky hypoxickém myokardu: vliv inhibitorů Author(s) Hlaváčková, M. (CZ)
Neckář, Jan (FGU-C) RID, ORCID
Nováková, O. (CZ)
Kolář, František (FGU-C) RID, ORCID, SAI
Musters, R.J.P. (NL)
Novák, F. (CZ)Source Title Nitric oxide signaling pathways. - Bratislava : Advent-Orion, 2007 / Pecháňová Olga - ISBN 978-80-8071-094-1 Pages s. 53-58 Number of pages 6 s. Number of copy 250 Number of pages 145 Language eng - English Country SK - Slovakia Keywords chronic hypoxia ; heart ; proteinkinase C Subject RIV FA - Cardiovascular Diseases incl. Cardiotharic Surgery R&D Projects GA305/07/0875 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50110509 - FGU-C (2005-2011) Annotation The aim of study was to analyzed acute effects of proteinkinase C (PKC) inhibitors on the expression and subcellular localization of PKC isoforms δ and ε in normoxic and chronically hypoxic rat hearts. The results of study are in line with negative effects of PKC inhibitors on the increased ischemic tolerance of chronically hypoxic hearts and support the view that PKC plays a role in this long-term cardioprotective mechanism Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2009
Number of the records: 1