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Circadian and developmental regulation of N-methyl-d-aspartate-receptor 1 mRNA splice variants and N-methyl-d-aspartate-receptor 3 subunit expression within the rat suprachiasmatic nucleus
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SYSNO ASEP 0323673 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Circadian and developmental regulation of N-methyl-d-aspartate-receptor 1 mRNA splice variants and N-methyl-d-aspartate-receptor 3 subunit expression within the rat suprachiasmatic nucleus Title Cirkadiánní a vývojová regulace sestřihových variant N-metyl-d-apartátového receptoru 1 mRNA a exprese podjednotek N-metyl-d-apartátového receptoru 3 v suprachiasmatických jádrech laboratorního potkana Author(s) Bendová, Zdeňka (FGU-C)
Sumová, Alena (FGU-C) RID, ORCID
Mikkelsen, J. D. (DK)Source Title Neuroscience. - : Elsevier - ISSN 0306-4522
Roč. 159, č. 2 (2009), s. 599-609Number of pages 11 s. Language eng - English Country GB - United Kingdom Keywords circadian clock ; ontogenesis ; photic entrainment Subject RIV FH - Neurology R&D Projects LC554 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GA309/08/0503 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000264162300015 DOI 10.1016/j.neuroscience.2009.01.016 Annotation We report the circadian expression of the NMDAR1 subunit in the adult rat suprachiasmatic nucleus (SCN) and depict its splice variants that may constitute the functional receptor channel. During ontogenesis, expression of two of the NMDAR1 subunit splice variants, as well as the NMDAR3A and 3B subunits, exhibits developmental loss around the time of eye opening. Moreover, the spatial and developmental characteristics of subunit NR1-E were demonstrated Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2009
Number of the records: 1