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Polymeric nanomedicines for radiochemotherapy
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SYSNO ASEP 0322152 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Polymeric nanomedicines for radiochemotherapy Title Polymerní nanoterapeutika pro radiochemoterapii Author(s) Lammers, T. (DE)
Šubr, Vladimír (UMCH-V) RID, ORCID
Ulbrich, Karel (UMCH-V) RID
Peschke, P. (DE)
Huber, P. E. (DE)
Hennink, W. E. (NL)
Storm, G. (NL)Source Title 14th International Symposium on Recent Advances in Drug Delivery Systems. - Salt Lake City : University of Utah, 2009 Pages s. 187-188 Number of pages 2 s. Action International Symposium on Recent Advances in Drug Delivery Systems /14./ Event date 15.02.2009-18.02.2009 VEvent location Salt Lake City Country US - United States Event type WRD Language eng - English Country US - United States Keywords HPMA copolymers ; drug deliver ; drug carriers Subject RIV CD - Macromolecular Chemistry CEZ AV0Z40500505 - UMCH-V (2005-2011) Annotation 131I and Gd-labeled HPMA copolymers of different sizes circulate in bloodstream for prolonged period of time and accumulate in solid tumors more effectively than in healthy tissues confirming their selective accumulation in tumors due to EPR effect. The effect of combination of chemotherapy and radiotherapy on the tumor accumulation is significant resulting in increase of concentration of the polymer therapeutics in the tumor and in its antitumor effect without any signs of side toxicity. Workplace Institute of Macromolecular Chemistry Contact Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Year of Publishing 2009
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