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Mechanism of Pro-Oxidant and Antioxidant Properties of Mitochondrial Matrix-Targeted Ubiquinone MitoQ10

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    SYSNO ASEP0321672
    Document TypeA - Abstract
    R&D Document TypeThe record was not marked in the RIV
    R&D Document TypeNení vybrán druh dokumentu
    TitleMechanism of Pro-Oxidant and Antioxidant Properties of Mitochondrial Matrix-Targeted Ubiquinone MitoQ10
    TitleMechanizmus Pro-Oxydativních a Antioxydativních vlastností do Mitochondriální Matrix Cíleného Ubichinonu MitoQ10
    Author(s) Plecitá-Hlavatá, Lydie (FGU-C) RID, ORCID
    Ježek, Jan (FGU-C) RID, ORCID
    Ježek, Petr (FGU-C) RID, ORCID
    Source TitleFree Radical Biology and Medicine. - : Elsevier - ISSN 0891-5849
    Roč. 45, Suppl.1 (2008), S85-S85
    Number of pages1 s.
    ActionSFRBM's Annual Meeting /15./
    Event date19.11.2008-23.11.2008
    VEvent locationIndianapolis
    CountryUS - United States
    Event typeWRD
    Languageeng - English
    CountryUS - United States
    Keywordscpo1 ; Ubiquinone MitoQ10 ; superoxide generation ; HEP-G2 cells
    Subject RIVCE - Biochemistry
    R&D ProjectsNR9183 GA MZd - Ministry of Health (MZ)
    IAA500110701 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    GA303/07/0105 GA ČR - Czech Science Foundation (CSF)
    1P05ME794 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
    CEZAV0Z50110509 - FGU-C (2005-2011)
    AnnotationMitoQ10 possesses a pro-oxidant role when added to intact mitochondrial respiratory chain. Its antioxidant role is striking when Complex I- derived superoxide generation increases due to retardation of electron flow within the Complex I
    WorkplaceInstitute of Physiology
    ContactLucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
    Year of Publishing2009
Number of the records: 1  

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