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Single-Voxel Short-Echo Time Proton Spectroscopy of Human Brain with Standard Surface Coils
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SYSNO ASEP 0205352 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Single-Voxel Short-Echo Time Proton Spectroscopy of Human Brain with Standard Surface Coils Author(s) Mlynárik, V. (AT)
Gruber, S. (AT)
Starčuk, Zenon (UPT-D) RID
Starčuk jr., Zenon (UPT-D) RID, ORCID, SAI
Roden, M. (AT)
Moser, E. (AT)Source Title Proceedings of 8th Scientific Meeting and Exhibition Magnetic Resonance in Medicine. - Denver : ISMRM, 2000 Pages s. 1857 Number of pages 1 s. Action ISMRM /8./ - Scientific Meeting and Exhibition Event date 01.04.2000-07.04.2000 VEvent location Denver Country US - United States Language eng - English Country US - United States Subject RIV JA - Electronics ; Optoelectronics, Electrical Engineering CEZ AV0Z2065902 - UPT-D Annotation In spite of the development of multi-voxel spectroscopy techniques, proton single voxel MR spectroscopy is still the method of choice in many clinical examinations of the human brain. For measuring spectra from the brain cortex, surface coils can be preferably used due to their higher sensitivity and lower power deposition compared to volume coils. However, surface coils used as a transmitter are limited by the inhomogeneous B1 field produced. This as a serious complication for pulse sequences that require well defined flip angles, especially for suppressing the strong water signal. Only a few reports on the measurement of proton spectra from the human brain using surface coils as transmitters appeared in the literature. In these papers, either a specially designed coil with a region of relatively homogenous B1 field was constructed or a combination of specific hardware and software was used for outer volume amd water suppression, with the aim of spectral editting of GABA. To our best knowledge, this is the first report on a single voxel STEAM spectrum of human brain produced solely by a standard surface coil. Efficient water suppression was achieved by a modification of the method originally proposed by de Graaf and Nicolay. Workplace Institute of Scientific Instruments Contact Martina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178 Year of Publishing 2001
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