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Combining combinatorial chemistry and affinity chromatography: highly selective inhibitors of human betaine:homocysteine S-methyltransferase

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    0194758 - UOCHB-X 20030063 RIV GB eng J - Journal Article
    Collinsová, Michaela - Castro, C. - Garrow, T. A. - Yiotakis, A. - Dive, V. - Jiráček, Jiří
    Combining combinatorial chemistry and affinity chromatography: highly selective inhibitors of human betaine:homocysteine S-methyltransferase.
    Chemistry & Biology. Roč. 10, - (2003), s. 113-122. ISSN 1074-5521
    R&D Projects: GA AV ČR IAB4055003
    Institutional research plan: CEZ:AV0Z4055905
    Keywords : BHMT * inhibitor * phosphinic
    Subject RIV: CE - Biochemistry
    Impact factor: 6.129, year: 2003

    A new method to find novel protein targets for ligands of interest is proposed. The principle of this approach is based on affinity chromatography and combinatorial chemistry.
    Permanent Link: http://hdl.handle.net/11104/0090429

     
     

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