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Cytostatic 6-arylpurine nucleosides III. Synthesis and structure-activity relationship study in cytostatic activity of 6-aryl-, 6-hetaryl- and 6-benzylpurine ribonucleosides
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SYSNO ASEP 0194121 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Cytostatic 6-arylpurine nucleosides III. Synthesis and structure-activity relationship study in cytostatic activity of 6-aryl-, 6-hetaryl- and 6-benzylpurine ribonucleosides Author(s) Hocek, Michal (UOCHB-X) RID, ORCID
Holý, Antonín (UOCHB-X)
Votruba, Ivan (UOCHB-X) RID
Dvořáková, H. (CZ)Source Title Collection of Czechoslovak Chemical Communications. - : Ústav organické chemie a biochemie AV ČR, v. v. i. - ISSN 0010-0765
Roč. 66, č. 3 (2001), s. 483-499Number of pages 17 s. Language eng - English Country CZ - Czech Republic Keywords purines ; nucleosides Subject RIV CC - Organic Chemistry R&D Projects GV203/96/K001 GA ČR - Czech Science Foundation (CSF) GA203/00/0036 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z4055905 - UOCHB-X Annotation A series of 6-aryl, 6-hetaryl and 6-benzylpurine ribonucleosides has been prepared by Pd-catalyzed cross-coupling reactions of 6-chloro-9-(2,3,5-tri-.I.O./I.-acetyl-á-D-ribofuranosyl)-purine with arylboronic acid, hetarylzinc halides, hetarylstannanes or benzylzinc halides followed by deprotection. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Year of Publishing 2002
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