Mechanisms of light transmittance changes in rat spinal cord slices

0173631 - UEM-P 20023051 RIV US eng J - Journal Article
Vargová, Lýdia - Kubinová, Šárka - Syková, Eva
Mechanisms of light transmittance changes in rat spinal cord slices.
Glia. Roč. 1, č. 1 (2002), s. S36. ISSN 0894-1491. E-ISSN 1098-1136.
[European Meeting on Glial Cell Function in Health and Disease /5./. Rome - Italy, 21.05.2002-25.05.2002]
R&D Projects: GA MŠMT LN00A065
Institutional research plan: CEZ:AV0Z5039906; CEZ:MSM 111100004; CEZ:MSM 5011112
Keywords : light transmittance changes
Subject RIV: FH - Neurology
Impact factor: 4.600, year: 2002

To test the hypothesis that changes in intrinsic optical signals (IOS) correspond to activity-related cell swelling, we simultaneously measurd changes in light transmittance (LT) and extracellular space diffusion parameters (ACS-DP) evoked by a 45 min application of hypotonic solutions or elevated K+ in spinal cord slices of 910-day-old-rats. We conclude that an LT increase is not directly related to cell swelling, but ratherto fine structural changes corresponding to K+-evoked neuronal activity.
Permanent Link: http://hdl.handle.net/11104/0070660